BIOPEP-UWM: Peptide Data
ID
Name
Sequence
VLIVP
Chemical Mass
Number of residues
Monoisotopic Mass
EC50
IC50
µM
Function Information
This peptide was synthesized using solid-phase FMOC chemistry. The IC50 for ACE inhibition was 1.69 ± 0.17 micromole. The synthetic peptide was a potent competitive inhibitor of ACE with a Ki of 4.5 ± 0.25 × 10-6 M. This peptide was resistant to digestion by proteases of the gastrointestinal tract. The antihypertensive property of this peptide derived from glycinin might find importance in the development of therapeutic functional foods.
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