BIOPEP-UWM: Peptide Data
ID
Name
Sequence
RPKPQQFFGLMG
Chemical Mass
Number of residues
Monoisotopic Mass
EC50
IC50
µM
Additional Information
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCCN)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCSC)C(=O)NCC(=O)O InChI=1S/C65H100N18O15S/c1-38(2)33-46(59(93)77-44(27-32-99-3)55(89)74-37-54(87)88)75-53(86)36-73-56(90)47(34-39-15-6-4-7-16-39)80-60(94)48(35-40-17-8-5-9-18-40)81-58(92)42(23-25-51(68)84)76-57(91)43(24-26-52(69)85)78-61(95)50-22-14-31-83(50)64(98)45(20-10-11-28-66)79-62(96)49-21-13-30-82(49)63(97)41(67)19-12-29-72-65(70)71/h4-9,15-18,38,41-50H,10-14,19-37,66-67H2,1-3H3,(H2,68,84)(H2,69,85)(H,73,90)(H,74,89)(H,75,86)(H,76,91)(H,77,93)(H,78,95)(H,79,96)(H,80,94)(H,81,92)(H,87,88)(H4,70,71,72)/t41-,42-,43-,44-,45-,46-,47-,48-,49-,50-/m0/s1 InChIKey: WYMDHULEODCOGK-SARDKLJWSA-N The active form contains C-terminal amide group instead of C-terminal glycine residue. Peptide is the precursor of substancje P (ID 2674 in BIOPEP-UWM database of bioactive peptides). Reviews concerning C-terminal amidation of peptides: Bradbury A. F., Smyth D. G., 1991, Peptide amidation. Trends Biochem. Sci., 16, 112-115 Merkler D. J., 1994, C-terminal amidated peptides: production by the in vitro enzymatic amidation of glycine-extended peptides and the importance of the amide to bioactivity. Enzyme Microb. Technol., 16, 450-456
activity
references
function information
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list of peptides