BIOPEP-UWM: Peptide Data
ID
Name
Sequence
FLPLILRKIVTALG
Chemical Mass
Number of residues
Monoisotopic Mass
EC50
IC50
µM
Additional Information
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(Cc1ccccc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(O)=O InChI=1S/C76H132N18O16/c1-17-45(13)60(92-69(104)55(36-42(7)8)87-70(105)57-30-25-33-94(57)75(110)56(37-43(9)10)89-64(99)50(78)38-49-26-20-19-21-27-49)72(107)88-54(35-41(5)6)68(103)85-52(29-24-32-81-76(79)80)66(101)84-51(28-22-23-31-77)67(102)91-61(46(14)18-2)73(108)90-59(44(11)12)71(106)93-62(48(16)95)74(109)83-47(15)63(98)86-53(34-40(3)4)65(100)82-39-58(96)97/h19-21,26-27,40-48,50-57,59-62,95H,17-18,22-25,28-39,77-78H2,1-16H3,(H,82,100)(H,83,109)(H,84,101)(H,85,103)(H,86,98)(H,87,105)(H,88,107)(H,89,99)(H,90,108)(H,91,102)(H,92,104)(H,93,106)(H,96,97)(H4,79,80,81)/t45-,46-,47-,48+,50-,51-,52-,53-,54-,55-,56-,57-,59-,60-,61-,62-/m0/s1 InChIKey=UENXIFMCTFTBIM-ZHZJPZCESA-N The active form is C-terminal amide group instead of C-terminal glycine residue. Peptide is the precursor of hemolytic peptide (ID 3196 in BIOPEP-UWM database of bioactive peptides). Reviews concerning C-terminal amidation of peptides: Bradbury A. F., Smyth D. G., 1991, Peptide amidation. Trends Biochem. Sci., 16, 112-115 Merkler D. J., 1994, C-terminal amidated peptides: production by the in vitro enzymatic amidation of glycine-extended peptides and the importance of the amide to bioactivity. Enzyme Microb. Technol., 16, 450-456
activity
references
function information
database references
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list of peptides