BIOPEP-UWM: Peptide Data
ID
Name
Sequence
KWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAKG
Chemical Mass
Number of residues
Monoisotopic Mass
EC50
IC50
µM
Additional Information
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(CCCCN)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(O)=O)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)NCC(O)=O InChI=1S/C186H315N53O48/c1-27-99(16)147(184(286)237-151(103(20)31-5)183(285)220-116(59-39-46-76-189)161(263)208-104(21)153(255)206-92-139(248)239-82-52-65-131(239)175(277)210-107(24)155(257)230-145(97(12)13)178(280)211-108(25)156(258)231-146(98(14)15)179(281)233-144(96(10)11)177(279)205-89-136(245)213-122(66-70-132(195)241)162(264)209-106(23)157(259)238-152(109(26)240)185(287)223-124(68-72-134(197)243)170(272)234-148(100(17)28-2)180(282)212-105(22)154(256)215-115(58-38-45-75-188)159(261)207-93-142(253)254)229-138(247)91-203-160(262)130(87-141(251)252)228-165(267)121(64-51-81-201-186(199)200)221-181(283)150(102(19)30-4)236-174(276)129(86-135(198)244)227-166(268)123(67-71-133(196)242)214-137(246)90-204-176(278)143(95(8)9)232-168(270)119(62-42-49-79-192)217-167(269)125(69-73-140(249)250)222-182(284)149(101(18)29-3)235-169(271)120(63-43-50-80-193)216-163(265)117(60-40-47-77-190)218-172(274)127(84-110-53-33-32-34-54-110)226-171(273)126(83-94(6)7)225-164(266)118(61-41-48-78-191)219-173(275)128(224-158(260)113(194)56-37-44-74-187)85-111-88-202-114-57-36-35-55-112(111)114/h32-36,53-55,57,88,94-109,113,115-131,143-152,202,240H,27-31,37-52,56,58-87,89-93,187-194H2,1-26H3,(H2,195,241)(H2,196,242)(H2,197,243)(H2,198,244)(H,203,262)(H,204,278)(H,205,279)(H,206,255)(H,207,261)(H,208,263)(H,209,264)(H,210,277)(H,211,280)(H,212,282)(H,213,245)(H,214,246)(H,215,256)(H,216,265)(H,217,269)(H,218,274)(H,219,275)(H,220,285)(H,221,283)(H,222,284)(H,223,287)(H,224,260)(H,225,266)(H,226,273)(H,227,268)(H,228,267)(H,229,247)(H,230,257)(H,231,258)(H,232,270)(H,233,281)(H,234,272)(H,235,271)(H,236,276)(H,237,286)(H,238,259)(H,249,250)(H,251,252)(H,253,254)(H4,199,200,201)/t99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109+,113-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-/m0/s1 InChIKey=ORQDSHLJVRLFJQ-BRRRVCJNSA-N The active form is C-terminal amide group instead of C-terminal glycine residue. Peptide is the precursor of antibacterial peptide (ID 3212 in BIOPEP-UWM database of bioactive peptides). Reviews concerning C-terminal amidation of peptides: Bradbury A. F., Smyth D. G., 1991, Peptide amidation. Trends Biochem. Sci., 16, 112-115 Merkler D. J., 1994, C-terminal amidated peptides: production by the in vitro enzymatic amidation of glycine-extended peptides and the importance of the amide to bioactivity. Enzyme Microb. Technol., 16, 450-456
activity
references
function information
database references
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list of peptides