Untitled Document

BIOPEP-UWM: Peptide Data

ID		Name
Sequence	VF
	VF

Chemical Mass		Number of residues
Monoisotopic Mass			µM

Additional Information

BIOPEP-UWM database of bioactive peptides

SMILES: N[C@H](C(=O)N[C@H](C(=O)O)Cc1ccccc1)C(C)C

InChI=1S/C14H20N2O3/c1-9(2)12(15)13(17)16-11(14(18)19)8-10-6-4-3-5-7-10/h3-7,9,11-12H,8,15H2,1-2H3,(H,16,17)(H,18,19)/t11-,12-/m0/s1

InChIKey: GJNDXQBALKCYSZ-RYUDHWBXSA-N

Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-001

Another value of peptide IC50(EC50)=53 uM

Cushman D. W., 1981. Angiotensin converting enzyme inhibitors: Evolution of a new class of antihypertensive drugs (page 19). in: Horovitz Z. P. (Ed.)(1981), Mechanisms of action and clinical implications, Urban & Schwarzenberg.

Peptide found also in amaranth protein hydrolysate.

Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111

Inhibitor of Calpain 1 (EC 3.4.22.52) (MEROPS ID: C02.001) according to the BIOPEP-UWM database of bioactive peptides; the ChEMBL database; the PubChem database
Inhibitor of Tripeptidyl peptidase 2 (EC 3.4.14.10) (MEROPS ID S08.090) according to the BIOPEP-UWM database of bioactive peptides; the BRENDA database; the ChEMBL database; the PubChem database
Inhibitor of Neprilysin-2 (EC 3.4.24.B14) (MEROPS ID: M13.008) according to the BIOPEP-UWM database of bioactive peptides; the BRENDA database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8917)
Antiviral peptide according to the BIOPEP-UWM database of bioactive peptides; the ChEMBL database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 51)

screen and print peptide data

list of peptides

Bioactive peptides links	BIO 9918	BIO 8917	BIO 9920	BIO 10095
Sensory peptides and amino acids links	Sens 51