BIOPEP-UWM: Peptide Data
ID
Name
Sequence
GLFDIAKKVIGVIGSLG
Chemical Mass
Number of residues
Monoisotopic Mass
EC50
IC50
µM
Additional Information
BIOPEP-UWM database of bioactive peptides SMILES: [[H][C@](C)(CC)[C@]([H])(NC(=O)[C@@]([H])(NC(=O)CNC(=O)[C@@]([H])(NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(C)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]([H])(Cc1ccccc1)NC(=O)[C@]([H])(CC(C)C)NC(=O)CN)[C@@]([H])(C)CC)C(C)C)[C@@]([H])(C)CC)C(C)C)C(=O)NCC(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(O)=O InChI=1S/C79H135N19O21/c1-16-45(12)64(75(115)83-37-58(101)88-56(40-99)74(114)91-52(32-41(4)5)68(108)85-39-61(105)106)97-77(117)62(43(8)9)94-59(102)38-84-76(116)65(46(13)17-2)98-78(118)63(44(10)11)95-70(110)51(29-23-25-31-81)90-69(109)50(28-22-24-30-80)89-67(107)48(15)86-79(119)66(47(14)18-3)96-73(113)55(35-60(103)104)93-72(112)54(34-49-26-20-19-21-27-49)92-71(111)53(33-42(6)7)87-57(100)36-82/h19-21,26-27,41-48,50-56,62-66,99H,16-18,22-25,28-40,80-82H2,1-15H3,(H,83,115)(H,84,116)(H,85,108)(H,86,119)(H,87,100)(H,88,101)(H,89,107)(H,90,109)(H,91,114)(H,92,111)(H,93,112)(H,94,102)(H,95,110)(H,96,113)(H,97,117)(H,98,118)(H,103,104)(H,105,106)/t45-,46-,47-,48-,50-,51-,52-,53-,54-,55-,56-,62-,63-,64-,65-,66-/m0/s1 InChIKey=JEUMNSAPJFDPRK-OEYHWHAPSA-N The active form is C-terminal amide group instead of C-terminal glycine residue. Peptide is the precursor of Aurein 2.6 (ID 3933 and 7046 in BIOPEP-UWM database of bioactive peptides). Reviews concerning C-terminal amidation of peptides: Bradbury A. F., Smyth D. G., 1991, Peptide amidation. Trends Biochem. Sci., 16, 112-115 Merkler D. J., 1994, C-terminal amidated peptides: production by the in vitro enzymatic amidation of glycine-extended peptides and the importance of the amide to bioactivity. Enzyme Microb. Technol., 16, 450-456
activity
references
function information
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list of peptides