BIOPEP-UWM: Peptide Data
ID
Name
Sequence
GLFDIVKKVVGAFGSLG
Chemical Mass
Number of residues
Monoisotopic Mass
EC50
IC50
µM
Additional Information
BIOPEP-UWM database of bioactive peptides SMILES: NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@H](CC)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)O InChI=1S/C81H131N19O21/c1-14-48(12)68(100-76(116)58(37-63(105)106)96-75(115)57(36-51-27-19-16-20-28-51)95-74(114)55(34-44(4)5)89-60(102)38-84)81(121)99-66(46(8)9)79(119)92-52(29-21-23-31-82)72(112)91-53(30-22-24-32-83)73(113)97-67(47(10)11)80(120)98-65(45(6)7)78(118)86-39-61(103)88-49(13)69(109)93-56(35-50-25-17-15-18-26-50)71(111)85-40-62(104)90-59(42-101)77(117)94-54(33-43(2)3)70(110)87-41-64(107)108/h15-20,25-28,43-49,52-59,65-68,101H,14,21-24,29-42,82-84H2,1-13H3,(H,85,111)(H,86,118)(H,87,110)(H,88,103)(H,89,102)(H,90,104)(H,91,112)(H,92,119)(H,93,109)(H,94,117)(H,95,114)(H,96,115)(H,97,113)(H,98,120)(H,99,121)(H,100,116)(H,105,106)(H,107,108)/t48-,49-,52-,53-,54-,55-,56-,57-,58-,59-,65-,66-,67-,68-/m0/s1 InChIKey: KGZDDOMPOQVGAP-SLKHJCTPSA-N The active form is C-terminal amide group instead of C-terminal glycine residue. Peptide is the precursor of antibacterial and anticancer peptide (ID 5318 and 7045 respectively in BIOPEP-UWM database of bioactive peptides). Reviews concerning C-terminal amidation of peptides: Bradbury A. F., Smyth D. G., 1991, Peptide amidation. Trends Biochem. Sci., 16, 112-115 Merkler D. J., 1994, C-terminal amidated peptides: production by the in vitro enzymatic amidation of glycine-extended peptides and the importance of the amide to bioactivity. Enzyme Microb. Technol., 16, 450-456
activity
references
function information
database references
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list of peptides