BIOPEP-UWM: Peptide Data
ID
Name
Sequence
YKLFKKILKVLG
Chemical Mass
Number of residues
Monoisotopic Mass
EC50
IC50
µM
Additional Information
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(O)=O InChI=1S/C73H124N16O14/c1-11-47(10)62(73(103)87-58(39-45(6)7)69(99)83-54(27-17-21-35-76)67(97)88-61(46(8)9)72(102)86-56(37-43(2)3)64(94)79-42-60(91)92)89-68(98)55(28-18-22-36-77)81-65(95)53(26-16-20-34-75)82-71(101)59(41-48-23-13-12-14-24-48)85-70(100)57(38-44(4)5)84-66(96)52(25-15-19-33-74)80-63(93)51(78)40-49-29-31-50(90)32-30-49/h12-14,23-24,29-32,43-47,51-59,61-62,90H,11,15-22,25-28,33-42,74-78H2,1-10H3,(H,79,94)(H,80,93)(H,81,95)(H,82,101)(H,83,99)(H,84,96)(H,85,100)(H,86,102)(H,87,103)(H,88,97)(H,89,98)(H,91,92)/t47-,51-,52-,53-,54-,55-,56-,57-,58-,59-,61-,62-/m0/s1 InChIKey: OPMZPLMSSOWIFI-RJBXKHODSA-N The active form is C-terminal amide group instead of C-terminal glycine residue. Peptide is the precursor of antifungal one (ID 9286 in BIOPEP-UWM database of bioactive peptides). Reviews concerning C-terminal amidation of peptides: Bradbury A. F., Smyth D. G., 1991, Peptide amidation. Trends Biochem. Sci., 16, 112-115 Merkler D. J., 1994, C-terminal amidated peptides: production by the in vitro enzymatic amidation of glycine-extended peptides and the importance of the amide to bioactivity. Enzyme Microb. Technol., 16, 450-456
activity
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