BIOPEP-UWM: Peptide Data
ID
Name
Sequence
KKLFKKILKVLG
Chemical Mass
Number of residues
Monoisotopic Mass
EC50
IC50
µM
Additional Information
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(O)=O InChI=1S/C70H127N17O13/c1-11-46(10)59(70(100)85-55(39-44(6)7)66(96)81-51(30-18-23-35-74)64(94)86-58(45(8)9)69(99)84-53(37-42(2)3)61(91)77-41-57(88)89)87-65(95)52(31-19-24-36-75)79-62(92)50(29-17-22-34-73)80-68(98)56(40-47-25-13-12-14-26-47)83-67(97)54(38-43(4)5)82-63(93)49(28-16-21-33-72)78-60(90)48(76)27-15-20-32-71/h12-14,25-26,42-46,48-56,58-59H,11,15-24,27-41,71-76H2,1-10H3,(H,77,91)(H,78,90)(H,79,92)(H,80,98)(H,81,96)(H,82,93)(H,83,97)(H,84,99)(H,85,100)(H,86,94)(H,87,95)(H,88,89)/t46-,48-,49-,50-,51-,52-,53-,54-,55-,56-,58-,59-/m0/s1 InChIKey: PMPDXXLVQZEHJG-RFONBVJKSA-N The active form is C-terminal amide group instead of C-terminal glycine residue. Peptide is the precursor of hemolytic one (ID 9290 in BIOPEP-UWM database of bioactive peptides). Reviews concerning C-terminal amidation of peptides: Bradbury A. F., Smyth D. G., 1991, Peptide amidation. Trends Biochem. Sci., 16, 112-115 Merkler D. J., 1994, C-terminal amidated peptides: production by the in vitro enzymatic amidation of glycine-extended peptides and the importance of the amide to bioactivity. Enzyme Microb. Technol., 16, 450-456 Precursor of antifungal peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9310)
activity
references
function information
database references
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list of peptides