BIOPEP-UWM: Peptide Data
ID
Name
Sequence
KKLFKKILKFLG
Chemical Mass
Number of residues
Monoisotopic Mass
EC50
IC50
µM
Additional Information
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(O)=O InChI=1S/C74H127N17O13/c1-9-49(8)63(74(104)90-59(42-48(6)7)70(100)84-55(33-19-24-38-78)68(98)88-61(44-51-28-14-11-15-29-51)73(103)86-57(40-46(2)3)65(95)81-45-62(92)93)91-69(99)56(34-20-25-39-79)83-66(96)54(32-18-23-37-77)85-72(102)60(43-50-26-12-10-13-27-50)89-71(101)58(41-47(4)5)87-67(97)53(31-17-22-36-76)82-64(94)52(80)30-16-21-35-75/h10-15,26-29,46-49,52-61,63H,9,16-25,30-45,75-80H2,1-8H3,(H,81,95)(H,82,94)(H,83,96)(H,84,100)(H,85,102)(H,86,103)(H,87,97)(H,88,98)(H,89,101)(H,90,104)(H,91,99)(H,92,93)/t49-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,63-/m0/s1 InChIKey: ZNBQSKUSUMWIQN-UKORBUKFSA-N The active form is C-terminal amide group instead of C-terminal glycine residue. Peptide is the precursor of hemolytic one (ID 9303 in BIOPEP-UWM database of bioactive peptides). Reviews concerning C-terminal amidation of peptides: Bradbury A. F., Smyth D. G., 1991, Peptide amidation. Trends Biochem. Sci., 16, 112-115 Merkler D. J., 1994, C-terminal amidated peptides: production by the in vitro enzymatic amidation of glycine-extended peptides and the importance of the amide to bioactivity. Enzyme Microb. Technol., 16, 450-456 Precursor of antifungal peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9323)
activity
references
function information
database references
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list of peptides