BIOPEP-UWM: Report

ID 10028
Name Inhibitor od Dipeptidyl Peptidase IV
sequence
FF

Function:
Inhibitor od Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
2
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 312.3622 Monoisotopic mass 312.1469
IC50 :
730.00 µM



Bibliographic data:
Authors
Neves A. C., Harnedy P. A., O’Keeffe M. B., FitzGerald R. J.
Title
Bioactive peptides from Atlantic salmon (Salmo salar) with angiotensin converting enzyme and dipeptidyl peptidase IV inhibitory, and antioxidant activities. Food Chem., 218, 396-405, 2017
Year Source
2017 Journal



Additional information:
BIOPEP-UWM database of bioactive pepetides


SMILES: c1ccc(cc1)C[C@@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)O)N

InChI=1S/C18H20N2O3/c19-15(11-13-7-3-1-4-8-13)17(21)20-16(18(22)23)12-14-9-5-2-6-10-14/h1-10,15-16H,11-12,19H2,(H,20,21)(H,22,23)/t15-,16-/m0/s1

InChIKey: GKZIWHRNKRBEOH-HOTGVXAUSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Inhibitor of angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 10027); the EROP-Moscow database
Inhibitor of Pseudolysin (EC 3.4.24.26) (MEROPS ID: M04.005) according to BRENDA database
Inhibitor of Peptide transporting ATP-ase (EC 3.6.3.43) according to BRENDA database
Antimicrobial peptide according to the ParaPep database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 9)



Database reference:
AHTPDB: ID 3879; 5404

BIOPEP-UWM database of bioactive peptides: ID 10027

BIOPEP-UWM database of sensory peptides and amino acids: ID 9

BRENDA: Ligand Phe-Phe

CHEBI: ID 72723

ChemSpider: ID 5361193

EROP-Moscow database: ID E24050

FooDB: ID FDB029369

HMDB: ID HMDB0013302

J-GLOBAL: ID 200907064405220979

Nikkaji: ID J192.083

ParaPep: ID 1166

PubChem: ID 6993090

SATPdb: ID satpdb13383

ZINC: ID ZINC01605264