BIOPEP-UWM: Report

ID 10059
Name ACE inhibitor
sequence
YLGYLE
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 756.8403 Monoisotopic mass 756.3681
IC50 :
85.76 µM


Bibliographic data:
Authors
Amigo L., Martínez-Maqueda D., Hernández-Ledesma B.
Title
In silico and in vitro analysis of multifunctionality of animal food-derived peptides. Foods, 9, 991, 2020
Year Source
2020 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCC(O)=O)C(O)=O

InChI=1S/C37H52N6O11/c1-20(2)15-28(42-33(49)26(38)17-22-5-9-24(44)10-6-22)34(50)39-19-31(46)40-30(18-23-7-11-25(45)12-8-23)36(52)43-29(16-21(3)4)35(51)41-27(37(53)54)13-14-32(47)48/h5-12,20-21,26-30,44-45H,13-19,38H2,1-4H3,(H,39,50)(H,40,46)(H,41,51)(H,42,49)(H,43,52)(H,47,48)(H,53,54)/t26-,27-,28-,29-,30-/m0/s1

InChIKey=LEDKTLOMOHNIFX-IIZANFQQSA-N


Opioid peptide according to the BIOPEP-UWM database of bioactive peptides (ID 3265); the MBPDB database
Peptide stimulating mucin secretion in intestinal cells according to the BIOPEP-UWM database of bioactive peptides (ID 8338), the MBPDB database
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10057); the MBPDB database


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 3265; 8338; 10057

ChemSpider: ID 8366175

EPA-DSSTox: ID DTXSID50436517

EROP-Moscow: ID E14751

FeptideDB: ID 3265

MBPDB: Peptide YLGYLE

PepBank: Peptide YLGYLE

PubChem: CID 10190674