BIOPEP-UWM: Report

ID 10076
Name ACE inhibitor
sequence
IAF

Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 349.4236 Monoisotopic mass 349.1995
IC50 :
19.87 µM



Bibliographic data:
Authors
Liang F., Shi Y., Shi J., Zhang T., Zhang R.
Title
A novel angiotensin‑I‑converting enzyme (ACE) inhibitory peptide IAF (Ile‑Ala‑Phe) from pumpkin seed proteins: in silico screening, inhibitory activity, and molecular mechanisms. Eur. Food Res. Technol., 247, 2227–2237,
Year Source
2021 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@H]([C@H](CC)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O

InChI=1S/C18H27N3O4/c1-4-11(2)15(19)17(23)20-12(3)16(22)21-14(18(24)25)10-13-8-6-5-7-9-13/h5-9,11-12,14-15H,4,10,19H2,1-3H3,(H,20,23)(H,21,22)(H,24,25)/t11-,12-,14-,15-/m0/s1

InChIKey=DPTBVFUDCPINIP-JURCDPSOSA-N


Inhibitor of HMG-CoA reductase (EC 1.1.1.34) according to the BIOPEP-UWM database of bioactive peptides (ID 10235)



Database reference:
BIOPEP-UWM database of bioactive peptides: ID

ChEBI: ID 158152

PubChem: CID 656985