BIOPEP-UWM: Report

ID 10082
Name ACE inhibitor
sequence
ETSGMKPTEL
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
10
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 1092.2188 Monoisotopic mass 1091.5150
IC50 :
2.15 µM


Bibliographic data:
Authors
Nuchprapha A. Paisansak S., Sangtanoo P., Srimongkol P., Saisavoey T., Reamtong O., Choowongkomond K., Karnchanatat A.
Title
Two novel ACE inhibitory peptides isolated from longan seeds: purification, inhibitory kinetics and mechanisms. RSC Adv., 10, 12711-12720, 2020
Year Source
2020 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides



SMILES: N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CO)C(=O)NCC(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CCCCN)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)O

InChI=1S/C45H77N11O18S/c1-22(2)19-29(45(73)74)52-39(67)26(12-14-34(63)64)50-42(70)36(24(4)59)55-41(69)31-10-8-17-56(31)44(72)28(9-6-7-16-46)51-40(68)27(15-18-75-5)49-32(60)20-48-38(66)30(21-57)53-43(71)35(23(3)58)54-37(65)25(47)11-13-33(61)62/h22-31,35-36,57-59H,6-21,46-47H2,1-5H3,(H,48,66)(H,49,60)(H,50,70)(H,51,68)(H,52,67)(H,53,71)(H,54,65)(H,55,69)(H,61,62)(H,63,64)(H,73,74)/t23-,24-,25+,26+,27+,28+,29+,30+,31+,35+,36+/m1/s1

InChIKey=AXEAQAKRNAOWET-VLTGQLKZSA-N


Database reference: