BIOPEP-UWM: Report

ID 10097
Name Hypotensive peptide
sequence
LPLP

Function:
Antihypertensive activity in vivo in rats.
 
Number of residues
4
Activity code
hyp
Activity :
hypotensive
Chemical mass 438.5594 Monoisotopic mass 438.2833
EC50 :
0.00 µM



Bibliographic data:
Authors
Sanchez-Rivera L., Ferreira Santos P., Miralles B., Carron R., Montero J., Recio I.
Title
Peptide fragments from beta-casein f(134–138), HLPLP, generated by the action of rat blood plasma peptidases show potent antihypertensive activity. Food Res. Int., 88, 348-353, 2016
Year Source
2016 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C22H38N4O5/c1-13(2)11-15(23)20(28)25-9-5-7-17(25)19(27)24-16(12-14(3)4)21(29)26-10-6-8-18(26)22(30)31/h13-18H,5-12,23H2,1-4H3,(H,24,27)(H,30,31)/t15-,16-,17-,18-/m0/s1

InChIKey: IFFNGVZLMXVQFA-XSLAGTTESA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 2665), the EROP-Moscow database, the MBPDB database



Database reference:
AHTPDB: ID 3455, 3666, 4454, 4891, 5290, 6000, 6328, 6786, 6825

BioPepDB: ID biopep00849

BIOPEP-UWM database of bioactive peptides: ID 2665

ChemSpider: ID 9815444

EROP-Moscow: ID E14609

FeptideDB: ID 2665

MBPDB: Peptide LPLP

PubChem: CID 11640703

SATPdb: ID satpdb19776