BIOPEP-UWM: Report

ID 10102
Name Alpha-glucosidase inhibitor
sequence
SQHISTAGMEASGTSNMKF
Function:
Inhibitor of alpha-glucosidase (EC 3.2.1.20)
 
Number of residues
19
Activity code
glui
Activity :
alpha-glucosidase inhibitor
Chemical mass 1984.1687 Monoisotopic mass 1982.8796
IC50 :
530.00 µM


Bibliographic data:
Authors
Liu L., Chen J., Li X.
Title
Novel peptides with α-glucosidase inhibitory activity from Changii radix hydrolysates. Process Biochem., 111, 200–206, 2021
Year Source
2021 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC1=C[N]([H])C=N1)C(=O)N[C@@H]([C@H](CC)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@H](O)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@H](O)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O

InChI=1S/C81H130N24O30S2/c1-9-38(2)62(104-75(128)51(28-44-30-86-37-89-44)97-71(124)47(18-20-57(84)112)93-67(120)45(83)33-106)78(131)101-56(36-109)77(130)105-64(42(6)111)79(132)91-39(3)65(118)87-31-59(114)92-49(22-25-136-7)72(125)95-48(19-21-61(116)117)69(122)90-40(4)66(119)100-54(34-107)68(121)88-32-60(115)103-63(41(5)110)80(133)102-55(35-108)76(129)98-52(29-58(85)113)74(127)96-50(23-26-137-8)73(126)94-46(17-13-14-24-82)70(123)99-53(81(134)135)27-43-15-11-10-12-16-43/h10-12,15-16,30,37-42,45-56,62-64,106-111H,9,13-14,17-29,31-36,82-83H2,1-8H3,(H2,84,112)(H2,85,113)(H,86,89)(H,87,118)(H,88,121)(H,90,122)(H,91,132)(H,92,114)(H,93,120)(H,94,126)(H,95,125)(H,96,127)(H,97,124)(H,98,129)(H,99,123)(H,100,119)(H,101,131)(H,102,133)(H,103,115)(H,104,128)(H,105,130)(H,116,117)(H,134,135)/t38-,39-,40-,41+,42+,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,62-,63-,64-/m0/s1

InChIKey=OFPFLODOBVOJEN-RXMATFEDSA-N


Database reference: