BIOPEP-UWM: Report

ID 10108
Name Dipeptidyl peptidase IV inhibitor
sequence
PGVLPVA

Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
7
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 651.7925 Monoisotopic mass 651.3943
IC50 :
392.00 µM



Bibliographic data:
Authors
Zhou T., Liu Z., Pei J., Pan D., Gao X., Dang Y., Zhao Y.
Title
Novel broccoli-derived peptides hydrolyzed by trypsin with dual-angiotensin I-converting enzymes and dipeptidyl peptidase-IV-inhibitory activities. J. Agric. Food Chem., 69, 10885–10892, 2021
Year Source
2021 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N1[C@@]([H])(CCC1)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)O

InChI=1S/C31H53N7O8/c1-16(2)14-21(35-29(43)24(17(3)4)36-23(39)15-33-26(40)20-10-8-12-32-20)30(44)38-13-9-11-22(38)27(41)37-25(18(5)6)28(42)34-19(7)31(45)46/h16-22,24-25,32H,8-15H2,1-7H3,(H,33,40)(H,34,42)(H,35,43)(H,36,39)(H,37,41)(H,45,46)/t19-,20-,21-,22-,24-,25-/m0/s1

InChIKey=XZIGAXACPBKCTM-BKWLFHPQSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
according to the BIOPEP-UWM database of bioactive peptides (ID 10107)



Database reference:
BIOPEP-UWM database of bioactive peptides: ID 10107