BIOPEP-UWM: Report

ID 10109
Name ACE inhibitor
sequence
YLYSPAY
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
7
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 875.9608 Monoisotopic mass 875.4051
IC50 :
8.52 µM


Bibliographic data:
Authors
Zhou T., Liu Z., Pei J., Pan D., Gao X., Dang Y., Zhao Y.
Title
Novel broccoli-derived peptides hydrolyzed by trypsin with dual-angiotensin I-converting enzymes and dipeptidyl peptidase-IV-inhibitory activities. J. Agric. Food Chem., 69, 10885–10892, 2021
Year Source
2021 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CO)C(=O)N3[C@@H](CCC3)C(=O)N[C@@H](C)C(=O)N[C@@H](CC4=CC=C(C=C4)O)C(=O)O

InChI=1S/C44H57N7O12/c1-24(2)19-33(47-39(57)32(45)20-26-6-12-29(53)13-7-26)40(58)48-34(21-27-8-14-30(54)15-9-27)41(59)50-36(23-52)43(61)51-18-4-5-37(51)42(60)46-25(3)38(56)49-35(44(62)63)22-28-10-16-31(55)17-11-28/h6-17,24-25,32-37,52-55H,4-5,18-23,45H2,1-3H3,(H,46,60)(H,47,57)(H,48,58)(H,49,56)(H,50,59)(H,62,63)/t25-,32-,33-,34-,35-,36-,37-/m0/s1

InChIKey=DRRQNXVHUXHWEP-JTOPVPOCSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
According to the BIOPEP-UWM database of bioactive peptides (ID 10110)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 10110