BIOPEP-UWM: Report

ID 10116
Name Antinociceptive peptide
sequence
RP
Function:
Antinociceptive
 
Number of residues
2
Activity code
ne
Activity :
neuropeptide
Chemical mass 271.3153 Monoisotopic mass 271.1640
EC50 :
0.00 µM


Bibliographic data:
Authors
Cain G. A., Christos T. E., Johnson A. L., Pottorf R. S., Tam S., Schmidt W. K.
Title
Identification of simpler analogs of neurotensin (9-13) which retain antinociceptive activity. Bioorg. Med. Chem. Lett., 3, 1767-1772, 1993
Year Source
1993 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: C1C[C@H](N(C1)C(=O)[C@H](CCCN=C(N)N)N)C(=O)O

InChI=1S/C11H21N5O3/c12-7(3-1-5-15-11(13)14)9(17)16-6-2-4-8(16)10(18)19/h7-8H,1-6,12H2,(H,18,19)(H4,13,14,15)/t7-,8-/m0/s1

InChIKey: LQJAALCCPOTJGB-YUMQZZPRSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database, the BIOPEP database of bioactive peptides (ID 7582), the ChEMBL database; the EROP-Moscow database
Affinity to neurotensin receptor according to the ChEMBL database; the PubChem database
Antiviral peptide according to the AVPdb database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP database of bioactive peptides (ID 8518)


Bitter peptide according to the BIOPEP database of sensory peptides and amino acids (ID 11)
Salty taste enhancing peptide according to the BIOPEP database of sensory peptides and amino acids (ID 419)


Database reference:
ACToR: ID 2418-69-1

AHTPDB: ID 1120; 1390; 1470; 1502; 2793; 3054; 3056; 3083; 3179; 3221; 3533; 3583; 3789; 4021; 4442; 4495; 4676; 5423; 5452; 5641; 5676; 6114; 6568

AVPdb: ID AVP1054

BIOPEP database of bioactive peptides: ID 7582; 8518; 10171

BIOPEP database of sensory peptides and amino acids: ID 11; 419

BRENDA: Ligand Arg-Pro

ChEMBL: ID CHEMBL48223

ChemIDplus: ID 002418691

ChemSpider: ID 133095

EROP-Moscow: ID E10402

PubChem: ID 151003

SATPdb: ID satpdb23927

ZINC: ID ZINC04899739