BIOPEP-UWM: Report

ID 10122
Name ACE inhibitor
sequence
FRVW

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
4
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 606.7141 Monoisotopic mass 606.3269
IC50 :
18.34 µM



Bibliographic data:
Authors
Li J., Su J., Chen M., Chen J., Ding W., Li Y., Yin H.
Title
Two novel potent ACEI peptides isolated from Pinctada fucata meat hydrolysates using in silico analysis: identification, screening and inhibitory mechanisms. RSC Adv., 11, 12172-12182, 2021
Year Source
2021 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=C[N]([H])C3=CC=CC=C23)C(=O)O

InChI=1S/C31H42N8O5/c1-18(2)26(29(42)38-25(30(43)44)16-20-17-36-23-12-7-6-11-21(20)23)39-28(41)24(13-8-14-35-31(33)34)37-27(40)22(32)15-19-9-4-3-5-10-19/h3-7,9-12,17-18,22,24-26,36H,8,13-16,32H2,1-2H3,(H,37,40)(H,38,42)(H,39,41)(H,43,44)(H4,33,34,35)/t22-,24-,25-,26-/m0/s1

InChIKey=VNYJHTHISNMSJM-GKXKVECMSA-N



Database reference: