BIOPEP-UWM: Report
| ID | 10132 |
| Name | ACE inhibitor |
| sequence |
| Function: | |||
| Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) | |||
| Number of residues | 3 |
Activity code | ah |
| Activity : | ACE inhibitor |
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| Chemical mass | 359.4841 | Monoisotopic mass | 359.1872 | |
| IC50 : | 15.80 µM |
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| Bibliographic data: | |
| Authors | |
| Lammi C., Boschin G., Bollati C., Arnoldi A., Galaverna G., Dellafiora L. | |
| Title | |
| A heuristic, computer-driven and top-down approach to identify novel bioactive peptides: a proof-of-principle on angiotensin I converting enzyme inhibitory peptides. Food Res. Int., 150 A, 110753, 2021 | |
| Year | Source |
| 2021 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCSC)C(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C16H29N3O4S/c1-10(2)9-11(17)14(20)18-12(6-8-24-3)15(21)19-7-4-5-13(19)16(22)23/h10-13H,4-9,17H2,1-3H3,(H,18,20)(H,22,23)/t11-,12-,13-/m0/s1 InChIKey=GNRPTBRHRRZCMA-AVGNSLFASA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001 IC50 measured using cel-based assay; 6.8 µM Lammi C., Boschin G., Bollati C., Arnoldi A., Galaverna G., Dellafiora L., 2021, A heuristic, computer-driven and top-down approach to identify novel bioactive peptides: a proof-of-principle on angiotensin I converting enzyme inhibitory peptides. Food Res. Int., 150 A, 110753 |
| Database reference: |