BIOPEP-UWM: Report

ID 10195
Name Hypotensive peptide
sequence
LVLPGE

Function:
Lowering blood pressure in rats
 
Number of residues
6
Activity code
hyp
Activity :
hypotensive
Chemical mass 626.7401 Monoisotopic mass 626.3627
EC50 :
0.00 µM



Bibliographic data:
Authors
Pei J., Hua Y., Zhou T., Gao X., Dang Y., Wang Y.
Title
Transport, in vivo antihypertensive effect, and pharmacokinetics of an angiotensin-converting enzyme (ACE) inhibitory peptide LVLPGE. J. Agric. Food Chem., 69, 2149–2156, 2021
Year Source
2021 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N[C@@]([H])(CCC(=O)O)C(=O)O

InChI=1S/C29H50N6O9/c1-15(2)12-18(30)25(39)34-24(17(5)6)27(41)33-20(13-16(3)4)28(42)35-11-7-8-21(35)26(40)31-14-22(36)32-19(29(43)44)9-10-23(37)38/h15-21,24H,7-14,30H2,1-6H3,(H,31,40)(H,32,36)(H,33,41)(H,34,39)(H,37,38)(H,43,44)/t18-,19-,20-,21-,24-/m0/s1

InChIKey=VLKYKEAXTIBHRI-TVJXPIDLSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 10196)



Database reference:
BIOPEP-UWM database of bioactive peptides: ID 10196