BIOPEP-UWM: Report

ID 10199
Name ACE inhibitor
sequence
PFPGPIPN

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
8
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 837.9591 Monoisotopic mass 837.4371
IC50 :
12.79 µM



Bibliographic data:
Authors
Lin K., Zhang L., Han X., Cheng D.
Title
Novel angiotensin I-converting enzyme inhibitory peptides from protease hydrolysates of Qula casein: Quantitative structure-activity relationship modeling and molecular docking study. J. Funct. Foods, 32, 266-277, 2017
Year Source
2017 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(=O)N)C(=O)O

InChI=1S/C41H59N9O10/c1-3-24(2)34(40(58)50-20-10-16-31(50)37(55)46-28(41(59)60)22-32(42)51)47-38(56)30-15-8-18-48(30)33(52)23-44-36(54)29-14-9-19-49(29)39(57)27(21-25-11-5-4-6-12-25)45-35(53)26-13-7-17-43-26/h4-6,11-12,24,26-31,34,43H,3,7-10,13-23H2,1-2H3,(H2,42,51)(H,44,54)(H,45,53)(H,46,55)(H,47,56)(H,59,60)/t24-,26-,27-,28-,29-,30-,31-,34-/m0/s1

InChIKey=HKCGEBVAGCUYDX-NSIGZTGPSA-N






Database reference: