BIOPEP-UWM: Report

ID 10213
Name Dipeptidyl peptidase IV (DPPIV) inhibitor
sequence
VPLVM
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
5
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 557.7455 Monoisotopic mass 557.3236
IC50 :
99.68 µM


Bibliographic data:
Authors
Pei J., Liu Z., Pan D., Zhao Y., Dang Y., Gao X.
Title
Transport, stability, and in vivo hypoglycemic effect of a broccoli-derived DPP-IV inhibitory peptide VPLVM. J. Agric. Food Chem., 70, 4934–4941, 2022
Year Source
2022 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCSC)C(=O)O

InChI=1S/C26H47N5O6S/c1-14(2)13-18(29-23(33)19-9-8-11-31(19)25(35)20(27)15(3)4)22(32)30-21(16(5)6)24(34)28-17(26(36)37)10-12-38-7/h14-21H,8-13,27H2,1-7H3,(H,28,34)(H,29,33)(H,30,32)(H,36,37)/t17-,18-,19-,20-,21-/m0/s1

InChIKey=WTUQPUDBBBAMBB-UDZSMLTASA-N


Antidiabetic peptide according to the BIOPEP-UWM database of bioactive peptides


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 10214