BIOPEP-UWM: Report

ID 10233
Name Dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
SAPRHGSLGFLPRK
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
14
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 1522.7484 Monoisotopic mass 1521.8504
IC50 :
23.44 µM


Bibliographic data:
Authors
Wang J., Xie Y., Luan Y., Guo T., Xiao S., Zeng X., Zhang S.
Title
Identification and dipeptidyl peptidase IV (DPP-IV) inhibitory activity verification of peptides from mouse lymphocytes. Food Sci. Human Wellness, 11, 1515-1526, 2022
Year Source
2022 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CO)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)NCC(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C68H111N23O17/c1-37(2)27-46(87-61(102)50(35-93)83-54(95)33-79-57(98)48(30-41-31-75-36-80-41)88-59(100)44(19-12-24-77-68(73)74)85-62(103)51-20-13-25-90(51)64(105)39(5)81-55(96)42(70)34-92)56(97)78-32-53(94)82-47(29-40-15-7-6-8-16-40)60(101)89-49(28-38(3)4)65(106)91-26-14-21-52(91)63(104)84-43(18-11-23-76-67(71)72)58(99)86-45(66(107)108)17-9-10-22-69/h6-8,15-16,31,36-39,42-52,92-93H,9-14,17-30,32-35,69-70H2,1-5H3,(H,75,80)(H,78,97)(H,79,98)(H,81,96)(H,82,94)(H,83,95)(H,84,104)(H,85,103)(H,86,99)(H,87,102)(H,88,100)(H,89,101)(H,107,108)(H4,71,72,76)(H4,73,74,77)/t39-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-/m0/s1

InChIKey=AQMSBAVARSXPMX-WAZINIRISA-N


Database reference: