BIOPEP-UWM: Report

ID 10235
Name HMG-CoA reductase inhibitor
sequence
IAF
Function:
Inhibitor of HMG-CoA reductase (EC 1.1.1.34)
 
Number of residues
3
Activity code
HMGi
Activity :
HMG-CoA reductase inhibitor
Chemical mass 349.4236 Monoisotopic mass 349.1995
EC50 :
0.00 µM


Bibliographic data:
Authors
Silva M., Philadelpho B., Santos J., Souza V., Souza C., Santiago V., Silva J., Souza C., Azeredo F.; Castilho M., Cilli E., Ferreira E.
Title
IAF, QGF, and QDF peptides exhibit cholesterol-lowering activity through a Statin-like HMG-CoA reductase regulation mechanism: in silico and in vitro approach. Int. J. Mol. Sci., 22, 11067, 2021
Year Source
2021 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@H]([C@H](CC)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O

InChI=1S/C18H27N3O4/c1-4-11(2)15(19)17(23)20-12(3)16(22)21-14(18(24)25)10-13-8-6-5-7-9-13/h5-9,11-12,14-15H,4,10,19H2,1-3H3,(H,20,23)(H,21,22)(H,24,25)/t11-,12-,14-,15-/m0/s1

InChIKey=DPTBVFUDCPINIP-JURCDPSOSA-N


Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 10176)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 10176

ChEBI: ID 158152

PubChem: CID 656985