BIOPEP-UWM: Report

ID 10236
Name HMG-CoA reductase inhibitor
sequence
QGF
Function:
Inhibitor of HMG-CoA reductase (EC 1.1.1.34)
 
Number of residues
3
Activity code
HMGi
Activity :
HMG-CoA reductase inhibitor
Chemical mass 350.3688 Monoisotopic mass 350.1585
EC50 :
0.00 µM


Bibliographic data:
Authors
Silva M., Philadelpho B., Santos J., Souza V., Souza C., Santiago V., Silva J., Souza C., Azeredo F.; Castilho M., Cilli E., Ferreira E.
Title
IAF, QGF, and QDF peptides exhibit cholesterol-lowering activity through a Statin-like HMG-CoA reductase regulation mechanism: in silico and in vitro approach. Int. J. Mol. Sci., 22, 11067, 2021
Year Source
2021 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(CCC(=O)N)C(=O)NCC(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C16H22N4O5/c17-11(6-7-13(18)21)15(23)19-9-14(22)20-12(16(24)25)8-10-4-2-1-3-5-10/h1-5,11-12H,6-9,17H2,(H2,18,21)(H,19,23)(H,20,22)(H,24,25)/t11-,12-/m0/s1

InChIKey=VGTDBGYFVWOQTI-RYUDHWBXSA-N


Database reference:
ChEBI: ID 162163

PubChem: CID 51037325

SureChEMBL: ID SCHEMBL10601764