BIOPEP-UWM: Report

ID 10272
Name ACE Inhibitor
sequence
MAIPPKK

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
7
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 784.0203 Monoisotopic mass 783.4662
IC50 :
0.00 µM



Bibliographic data:
Authors
Miguel M., Manso M. A., López-Fandiño R., Alonso M. J., Salaices M.
Title
Vascular effects and antihypertensive properties of κ-casein macropeptide. Int. Dairy J., 17, 1473-1477, 2007
Year Source
2007 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CCSC)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(O)=O

InChI=1S/C36H65N9O8S/c1-5-22(2)29(43-30(46)23(3)40-31(47)24(39)16-21-54-4)35(51)45-20-11-15-28(45)34(50)44-19-10-14-27(44)33(49)41-25(12-6-8-17-37)32(48)42-26(36(52)53)13-7-9-18-38/h22-29H,5-21,37-39H2,1-4H3,(H,40,47)(H,41,49)(H,42,48)(H,43,46)(H,52,53)/t22-,23-,24-,25-,26-,27-,28-,29-/m0/s1

InChIKey=VPSBOBSPUBWDAJ-PJYAFMLMSA-N


Hypotensive peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10273); the DFBP database; the MBPDB database
Antithrombotic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 3294); the DFBP database; the MBPDB database



Database reference:
AHTPDB: ID 1007; 1335; 1737; 4145; 4299; 4325; 5029

BioPepDB: ID biopep00946

BIOPEP-UWM database of bioactive peptides: ID 3294; 10273

DFBP: ID DFBPANHY0543; DFBPANTH0006; DFBPANTH0053; DFBPANTH0162; DFBPMUFU0393

EROP-Moscow: ID E09383

FeptideDB: ID 3294

MBPDB: peptide MAIPPKK

SATPdb: ID satpdb10517