BIOPEP-UWM: Report

ID 10279
Name Inhibitor of Xaa-Pro dipeptidyl-peptidase
sequence
VPL
Function:
Inhibitor of Xaa-Pro dipeptidyl-peptidase (EC 3.4.14.11) (MEROPS ID: S15.001)
 
Number of residues
3
Activity code
xaap
Activity :
xaa-pro inhibitor
Chemical mass 327.4180 Monoisotopic mass 327.2151
IC50 :
600.00 µM


Bibliographic data:
Authors
Rigolet P., Xi X. G., Rety S., Chich J.-F.
Title
The structural comparison of the bacterial PepX and human DPP-IV reveals sites for the design of inhibitors of PepX activity. FEBS J., 272, 2050-2059, 2005
Year Source
2005 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)O

InChI=1S/C16H29N3O4/c1-9(2)8-11(16(22)23)18-14(20)12-6-5-7-19(12)15(21)13(17)10(3)4/h9-13H,5-8,17H2,1-4H3,(H,18,20)(H,22,23)/t11-,12-,13-/m0/s1

InChIKey: NHXZRXLFOBFMDM-AVGNSLFASA-N


Inhibitor of Prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001) according to the BIOPEP-UWM database of bioactive peptides (ID 3166)
Peptide stimulating vasoactive substance release according to the BIOPEP-UWM database of bioactive peptides (ID 3350)
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8347)


Database reference:
ACToR: ID 90614-49-6

BIOPEP-UWM database of bioactive peptides: ID 3166, 3350, 8354

BRENDA: Ligand Diprotin B

ChemBank: ID KBio3_002896

ChEMBL: ID CHEMBL3039071

ChemSpider: ID 128973

EROP-Moscow: ID E09236

J-GLOBAL: ID 200907065809070136

Nikkaji: ID J168.832D

PubChem: CID 7408179

SureChEMBL: ID SCHEMBL3125140

ZINC: ID ZINC000004899506