BIOPEP-UWM: Report

ID 10312
Name Alpha-glucosidase inhibitor
sequence
RNPFVFAPTLLTVAAR
Function:
Inhibitor of alpha-glucosidase (EC 3.2.1.20)
 
Number of residues
16
Activity code
glui
Activity :
alpha-glucosidase inhibitor
Chemical mass 1773.0809 Monoisotopic mass 1772.0067
IC50 :
92.78 µM


Bibliographic data:
Authors
Hu S., Fan X., Qi P., Zhang X.
Title
Identification of anti-diabetes peptides from spirulina platensis. J Funct Foods, 56, 333–341, 2019
Year Source
2019 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C83H133N23O20/c1-41(2)36-54(70(114)96-55(37-42(3)4)71(115)103-65(49(13)108)78(122)102-62(43(5)6)75(119)93-45(9)66(110)92-46(10)67(111)95-53(81(125)126)29-21-33-91-83(88)89)98-77(121)64(48(12)107)104-74(118)60-31-22-34-105(60)79(123)47(11)94-69(113)56(38-50-24-16-14-17-25-50)99-76(120)63(44(7)8)101-72(116)57(39-51-26-18-15-19-27-51)97-73(117)59-30-23-35-106(59)80(124)58(40-61(85)109)100-68(112)52(84)28-20-32-90-82(86)87/h14-19,24-27,41-49,52-60,62-65,107-108H,20-23,28-40,84H2,1-13H3,(H2,85,109)(H,92,110)(H,93,119)(H,94,113)(H,95,111)(H,96,114)(H,97,117)(H,98,121)(H,99,120)(H,100,112)(H,101,116)(H,102,122)(H,103,115)(H,104,118)(H,125,126)(H4,86,87,90)(H4,88,89,91)/t45-,46-,47-,48+,49+,52-,53-,54-,55-,56-,57-,58-,59-,60-,62-,63-,64-,65-/m0/s1

InChIKey= VVQDKZBYMPCIAB-ZEBLLMSHSA-N


Database reference: