BIOPEP-UWM: Report

ID 10335
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
APLER
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
5
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 584.6639 Monoisotopic mass 584.3272
IC50 :
63.67 µM


Bibliographic data:
Authors
Harnedy-Rothwell P. A., McLaughlin C. M., O’Keeffe M. B., le Gouic A. v., Allsopp P. J., McSorley E. M., Sharkey S., Whooley J., McGovern B., et al.
Title
Identification and characterisation of peptides from a boarfish (capros aper) protein hydrolysate displaying in vitro dipeptidyl peptidase-IV (DPP-IV) inhibitory and insulinotropic activity. Food Research International, 131, 108989, 2020
Year Source
2020 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C25H44N8O8/c1-13(2)12-17(32-22(38)18-7-5-11-33(18)23(39)14(3)26)21(37)30-15(8-9-19(34)35)20(36)31-16(24(40)41)6-4-10-29-25(27)28/h13-18H,4-12,26H2,1-3H3,(H,30,37)(H,31,36)(H,32,38)(H,34,35)(H,40,41)(H4,27,28,29)/t14-,15-,16-,17-,18-/m0/s1

InChIKey= UMLWLNLONSFUJR-ATIWLJMLSA-N


Database reference: