BIOPEP-UWM: Report

ID 10354
Name ACE Inhibitor
sequence
QLADVSPAAFLTQQQLLPFYLHAM
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
24
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 2703.1117 Monoisotopic mass 2701.3893
IC50 :
174.43 µM


Bibliographic data:
Authors
Díaz-Gómez J. L., Neundorf I., López-Castillo L. M., Castorena-Torres F., Serna-Saldívar S. O., García-Lara S.
Title
In Silico Analysis and In Vitro Characterization of the Bioactive Profile of Three Novel Peptides Identified from 19 kDa α-Zein Sequences of Maize. Molecules, 25(22), 5405, 2020
Year Source
2020 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CO)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCSC)C(=O)O

InChI=1S/C126H192N30O34S/c1-62(2)49-83(144-107(170)78(127)37-41-96(128)160)111(174)135-71(16)106(169)143-91(58-100(164)165)119(182)153-101(67(11)12)122(185)152-93(60-157)125(188)156-47-25-31-94(156)120(183)137-68(13)103(166)134-69(14)105(168)142-87(54-73-27-21-19-22-28-73)115(178)147-86(52-65(7)8)118(181)154-102(72(17)158)123(186)140-81(40-44-99(131)163)109(172)138-79(38-42-97(129)161)108(171)139-80(39-43-98(130)162)110(173)145-85(51-64(5)6)114(177)151-92(53-66(9)10)124(187)155-46-26-32-95(155)121(184)150-89(55-74-29-23-20-24-30-74)117(180)148-88(56-75-33-35-77(159)36-34-75)116(179)146-84(50-63(3)4)113(176)149-90(57-76-59-132-61-133-76)112(175)136-70(15)104(167)141-82(126(189)190)45-48-191-18/h19-24,27-30,33-36,59,61-72,78-95,101-102,157-159H,25-26,31-32,37-58,60,127H2,1-18H3,(H2,128,160)(H2,129,161)(H2,130,162)(H2,131,163)(H,132,133)(H,134,166)(H,135,174)(H,136,175)(H,137,183)(H,138,172)(H,139,171)(H,140,186)(H,141,167)(H,142,168)(H,143,169)(H,144,170)(H,145,173)(H,146,179)(H,147,178)(H,148,180)(H,149,176)(H,150,184)(H,151,177)(H,152,185)(H,153,182)(H,154,181)(H,164,165)(H,189,190)/t68-,69-,70-,71-,72+,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,101-,102-/m0/s1


InChIKey= BXJGAGPYFPZQCV-VDBJZKJDSA-N


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 10343