BIOPEP-UWM: Report

ID 10432
Name Chemotactic peptide
sequence
{C1}MLF

Function:
Agonist of FPR2 receptor
 
Number of residues
4
Activity code
che
Activity :
chemotactic
Chemical mass 437.5528 Monoisotopic mass 437.1977
EC50 :
0.00 µM



Bibliographic data:
Authors
Freer R. J., Day A. R., Radding J. A., Schiffmann E., Aswanikumar S., Showell H. J., Becker E. L.
Title
Further studies on the structural requirements for synthetic peptide chemoattractants. Biochemistry, 19, 2404-2410, 1980
Year Source
1980 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C21H31N3O5S/c1-14(2)11-17(23-19(26)16(22-13-25)9-10-30-3)20(27)24-18(21(28)29)12-15-7-5-4-6-8-15/h4-8,13-14,16-18H,9-12H2,1-3H3,(H,22,25)(H,23,26)(H,24,27)(H,28,29)/t16-,17-,18-/m0/s1

InChIKey=PRQROPMIIGLWRP-BZSNNMDCSA-N


{C1} - Formic acid – N-terminal modification (BIOPEP-UWM repository of amino acids and modifications: ID 157)

Review: Prevete N., Liotti F., Marone G., Melillo R. M., de Paulis A., 2015, Formyl peptide receptors at the interface of inflammation, angiogenesis and tumor growth. Pharmacol. Res., 102, 184–191



Database reference:
BindingDB: ID 50050937

BRENDA: Ligand Ligand N-formyl-L-methionyl-L-leucyl-L-phenylalanine

CAS: Registry No 59880-97-6

ChEBI: ID 53490

EPA CompTox: ID DTXSID9041077

FDA SRS: ID LO6AVJ8RCE

IUPHAR/BPS: GtoPdb Ligand ID 1022

J-GLOBAL: ID 200907038760801450

KEGG: Ligand C11596

MeSH: Term N Formyl Methionyl Leucyl Phenylalanine

Metabolomics Workbench: ID 58635

Nikkaji: ID J245.920E

PubChem: CID 443295

SureChEMBL: ID SCHEMBL39529

ZINC: ID ZINC000004099172