BIOPEP-UWM: Report

ID 10454
Name Neuropeptide
sequence
RR

Function:
Antinociceptive peptide
 
Number of residues
2
Activity code
ne
Activity :
neuropeptide
Chemical mass 330.3856 Monoisotopic mass 330.2123
EC50 :
0.00 µM



Bibliographic data:
Authors
Cain G. A., Christos T. E., Johnson A. L., Pottorf R. S., Tam S., Schmidt W. K.
Title
Identification of simpler analogs of neurotensin(913) which retain antinociceptive activity. Bioorg. Med. Chem. Lett., 3, 1767-1772, 1993
Year Source
1993 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C12H26N8O3/c13-7(3-1-5-18-11(14)15)9(21)20-8(10(22)23)4-2-6-19-12(16)17/h7-8H,1-6,13H2,(H,20,21)(H,22,23)(H4,14,15,18)(H4,16,17,19)/t7-,8-/m0/s1

InChIKey=OMLWNBVRVJYMBQ-YUMQZZPRSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8889)
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 7741).
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the the BIOPEP-UWM database of bioactive peptides (ID 9485)
Inhibitor of Leucyltransferase (EC 2.3.2.6) according to the BRENDA database
Inhibitor of HIV-1 retropepsin (EC 3.4.23.16) (MEROPS ID: A02.001) according to the BRENDA database
Antinociceptive peptide according to the ChEMBL database
Antibacterial peptide according to the ChEMBL database
Hemolytic peptide according to the ChEMBL database


Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 2)



Database reference:
ACToR: ID 15483-27-9

AHTPDB: ID 3273; 3534; 4023; 4738; 5170; 5432; 6108; 6689

BindingDB: ID 50188488

BioPepDB: ID biopep01222

BIOPEP-UWM database of bioactive peptides: ID 7741; 8889; 9485

BIOPEP-UWM database of sensory peptides and amino acids: ID 2

BRENDA: Ligand Arg-Arg

CAS: Registry No 15483-27-9

ChEBI: ID CHEBI:73811

ChEMBL: ID CHEMBL296756

ChemIDplus: ID 15483-27-9

ChemSpider: ID 133932

CTD: ID 15483-27-9

DFBP: ID DFBPACEI1096; DFBPACEI1686

eChemPortal: ID 15483-27-9

EPA CompTox: ID DTXSID60165745

EPA DSSTox: ID DTXCID2088236

EROP-Moscow: ID E14727

HMDB: ID HMDB0028703

J-GLOBAL: ID 200907087384149330

MeSH: terms Arg-Arg; arginylarginine

Metabolights: ID MTBLC73811

Metabolomics Workbench: ID 78677

Nikkaji: ID J531.298A

PlantPepDB: ID PPepDB_182

PubChem: CID 151956

SATPdb: ID satpdb21704

SureChEMBL: ID SCHEMBL288599

ZINC: ID ZINC000005706877