BIOPEP-UWM: Report

ID 10467
Name ACE inhibitor
sequence
FKCRRW
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 895.0842 Monoisotopic mass 894.4634
IC50 :
26.70 µM


Bibliographic data:
Authors
Ruiz-Giménez P., Ibáñez A., Salom J. B., Marcos J. F., López-Díez J. J., Vallés S., Torregrosa G., Alborch E., Manzanares P.
Title
Antihypertensive properties of lactoferricin B-derived peptides. J. Agric. Food Chem., 58, 6721–6727, 2010
Year Source
2010 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O

InChI=1S/C41H62N14O7S/c42-17-7-6-14-29(51-34(56)27(43)20-24-10-2-1-3-11-24)37(59)55-33(23-63)38(60)53-30(15-8-18-48-40(44)45)35(57)52-31(16-9-19-49-41(46)47)36(58)54-32(39(61)62)21-25-22-50-28-13-5-4-12-26(25)28/h1-5,10-13,22,27,29-33,50,63H,6-9,14-21,23,42-43H2,(H,51,56)(H,52,57)(H,53,60)(H,54,58)(H,55,59)(H,61,62)(H4,44,45,48)(H4,46,47,49)/t27-,29-,30-,31-,32-,33-/m0/s1

InChIKey=CHUJNSSYBVSDKX-AOUUIGKNSA-N


Database reference:
MBPDB: peptide FKCRRW