BIOPEP-UWM: Report

ID 10481
Name Inhibitor of tripeptidyl peptidase II
sequence
GW
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
2
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 261.2759 Monoisotopic mass 261.1110
EC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O

InChI=1S/C13H15N3O3/c14-6-12(17)16-11(13(18)19)5-8-7-15-10-4-2-1-3-9(8)10/h1-4,7,11,15H,5-6,14H2,(H,16,17)(H,18,19)/t11-/m0/s1

InChIKey=AJHCSUXXECOXOY-NSHDSACASA-N


Inhibitor of Dipeptidyl peptidase IV (DPP IV) (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID: 8787)
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BindingDB database; the BIOPEP-UWM database of bioactive peptides (ID 7579); the BRENDA database; the ChEMBL database; the EROP-Moscow database
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090) according to the BRENDA database; the ChEMBL database


Bitter peptide according to the ChEMBL database


Database reference:
AHTPDB: ID 1267, 1418, 1888, 2743, 2846, 3351, 3495, 3785, 3842, 3937, 4446, 4491, 4664, 6207, 6565

BindingDB: ID 50188499

BIOPEP-UWM database of bioactive peptides: ID 7579, 8787

BRENDA: Ligand Gly-Trp

CAS: Registry No 2390-74-1

CHEBI: ID 73921

ChEMBL: ID CHEMBL299759

ChemSpider: ID 83223

DFBP: ID DFBPACEI1228

ECHA: ID 219-235-7

eChemPortal: ID 2390-74-1

EPA CompTox: ID DTXSID301315473

EROP-Moscow: ID E09037

FDA SRS: ID 35BKX0QF16

GSRS: ID 310513ff-0bb3-4266-8034-7c28ae2ca5bb

J-Global: ID 200907021832427001

MeSH: terms Gly-Trp, glycyl-L-tryptophan, glycyltryptophan

Metabolights: ID MTBLC73921

Metabolomics Workbench: ID 78813

Nikkaji: ID J151.152A

NIST Chemistry Webbook: Compound Glycyl-L-tryptophan

PlantPepDB: ID PPepDB_72

PubChem: CID 92181

SATPdb: ID satpdb11189

SureChEMBL: ID SCHEMBL1407979

UNII: ID 35BKX0QF16

ZINC: ID ZINC000001708201