BIOPEP-UWM: Report

ID 10500
Name Acetylcholinesterase inhibitor
sequence
DKKERG

Function:
Inhibitor of Acetylcholinesterase (EC 3.1.1.7)
 
Number of residues
6
Activity code
ache
Activity :
AChE inhibitor
Chemical mass 731.7961 Monoisotopic mass 731.3914
IC50 :
295.00 µM



Bibliographic data:
Authors
Asen N.D., Okagu O.D., Udenigwe C.C., Aluko R.E.
Title
In vitro inhibition of acetylcholinesterase activity by yellow field pea (Pisum sativum) protein-derived peptides as revealed by kinetics and molecular docking. Front. Nutr., 9, 2022
Year Source
2022 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)NCC(=O)O

InChI=1S/C29H53N11O11/c30-11-3-1-6-18(37-24(47)16(32)14-22(43)44)26(49)39-19(7-2-4-12-31)27(50)40-20(9-10-21(41)42)28(51)38-17(8-5-13-35-29(33)34)25(48)36-15-23(45)46/h16-20H,1-15,30-32H2,(H,36,48)(H,37,47)(H,38,51)(H,39,49)(H,40,50)(H,41,42)(H,43,44)(H,45,46)(H4,33,34,35)/t16-,17-,18-,19-,20-/m0/s1

InChIKey=XKIZTHBHRCCPAO-HVTWWXFQSA-N

The IC50 value was calculated in μmol/L.



Database reference: