BIOPEP-UWM: Report

ID 10502
Name Acetylcholinesterase inhibitor
sequence
KVSRDQ

Function:
Inhibitor of Acetylcholinesterase (EC 3.1.1.7)
 
Number of residues
6
Activity code
ache
Activity :
AChE inhibitor
Chemical mass 731.7961 Monoisotopic mass 731.3914
IC50 :
166.00 µM



Bibliographic data:
Authors
Asen N.D., Okagu O.D., Udenigwe C.C., Aluko R.E.
Title
In vitro inhibition of acetylcholinesterase activity by yellow field pea (Pisum sativum) protein-derived peptides as revealed by kinetics and molecular docking. Front. Nutr., 9, 2022
Year Source
2022 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)O

InChI=1S/C29H53N11O11/c1-14(2)22(40-23(45)15(31)6-3-4-10-30)27(49)39-19(13-41)26(48)36-16(7-5-11-35-29(33)34)24(46)38-18(12-21(43)44)25(47)37-17(28(50)51)8-9-20(32)42/h14-19,22,41H,3-13,30-31H2,1-2H3,(H2,32,42)(H,36,48)(H,37,47)(H,38,46)(H,39,49)(H,40,45)(H,43,44)(H,50,51)(H4,33,34,35)/t15-,16-,17-,18-,19-,22-/m0/s1

InChIKey=OBJDZISPWPBEDC-LXYCOOOUSA-N

The IC50 value was calculated in μmol/L.



Database reference: