BIOPEP-UWM: Report

ID 10546
Name Neprilysin inhibitor
sequence
FG
Function:
Inhibitor of Neprilysin (EC 3.4.24.11) (MEROPS ID: M13.001)
 
Number of residues
2
Activity code
nep
Activity :
neprilysin inhibitor
Chemical mass 222.2399 Monoisotopic mass 222.1001
IC50 :
0.00 µM


Bibliographic data:
Authors
Dion N., Cohen P., Crine P., Boileau G.
Title
Characterisation of neprilysin (EC 3.4.24.11) S2' subsite. FEBS Lett, 411, 140-144, 1997
Year Source
1997 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)NCC(=O)O)Cc1ccccc1

InChI=1S/C11H14N2O3/c12-9(11(16)13-7-10(14)15)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,16)(H,14,15)/t9-/m0/s1

InChiKey: GLUBLISJVJFHQS-VIFPVBQESA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 7605)

Bitter peptide according to the BIOPEP database of sensory peptides and amino acids (ID 18), the BitterDB database, the ChEMBL database, the EROP-Moscow database (ID E03702)


Database reference:
ACToR: ID 294-26-2

AHTPDB: ID 1483; 3058; 3144; 3238; 3479; 3809; 3876; 3907; 4415; 4515; 4674; 5412; 6591

BindingDB: ID 50139894

BioPepDB: ID biopep00236
BIOPEP-UWM database of bioactive peptides (ID 7605)

BIOPEP-UWM database of sensory peptides and amino acids: ID 18

BitterDB: ID 835

BRENDA: Ligand Phe-Gly

ChEBI: ID 73635

ChEMBL: ID CHEMBL417979

ChemSpider: ID 5360444

EROP-Moscow: ID E03702; E10395

FeptideDB: ID 7605

J-GLOBAL: ID 200907031969906344

MeSH: Term phenylalanylglycine; ID C040500

Metabolights: ID MTBLC73635

Nikkaji: ID J79.926B

PlantPepDB: ID PPepDB_2903

PubChem: CID 6992304

SATPdb: ID satpdb13141

SureChEMBL: ID SCHEMBL1329817

ZINC: ID ZINC01569733