BIOPEP-UWM: Report

ID 10550
Name ACE inhibitor
sequence
SRP

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 358.3924 Monoisotopic mass 358.1959
IC50 :
46.00 µM



Bibliographic data:
Authors
Cai X., Huang M., Huang X., Liu H., Wang T., Li L., Yang W., Luo H., Lu Y.
Title
Properties of ACE inhibitory peptides isolated from Sipunculus nudus L and a DSPE-PEG modification for sustained release anti-hypertension agent. Process Biochem., 127, 56–65, 2023
Year Source
2023 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C14H26N6O5/c15-8(7-21)11(22)19-9(3-1-5-18-14(16)17)12(23)20-6-2-4-10(20)13(24)25/h8-10,21H,1-7,15H2,(H,19,22)(H,24,25)(H4,16,17,18)/t8-,9-,10-/m0/s1

InChIKey=NRCJWSGXMAPYQX-GUBZILKMSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001




Database reference:
PubChem: CID 11990213