BIOPEP-UWM: Report

ID 10551
Name ACE inhibitor
sequence
PRP

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 368.4302 Monoisotopic mass 368.2166
IC50 :
420.00 µM



Bibliographic data:
Authors
Cai X., Huang M., Huang X., Liu H., Wang T., Li L., Yang W., Luo H., Lu Y.
Title
Properties of ACE inhibitory peptides isolated from Sipunculus nudus L and a DSPE-PEG modification for sustained release anti-hypertension agent. Process Biochem., 127, 56–65, 2023
Year Source
2023 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C16H28N6O4/c17-16(18)20-8-2-5-11(21-13(23)10-4-1-7-19-10)14(24)22-9-3-6-12(22)15(25)26/h10-12,19H,1-9H2,(H,21,23)(H,25,26)(H4,17,18,20)/t10-,11-,12-/m0/s1

InChIKey=ICTZKEXYDDZZFP-SRVKXCTJSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001





Database reference:
BRENDA: Ligand PRP

CAS: Registry No 56610-49-2

ChEBI: ID 144903

ChemSpider: ID 10162559

EPA CompTox: ID DTXSID00475330

PubChem: CID 11990092

SureChEMBL: ID SCHEMBL7351817