BIOPEP-UWM: Report

ID 10553
Name ACE inhibitor
sequence
LPK

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 356.4591 Monoisotopic mass 356.2416
IC50 :
6540.00 µM



Bibliographic data:
Authors
Cai X., Huang M., Huang X., Liu H., Wang T., Li L., Yang W., Luo H., Lu Y.
Title
Properties of ACE inhibitory peptides isolated from Sipunculus nudus L and a DSPE-PEG modification for sustained release anti-hypertension agent. Process Biochem., 127, 56–65, 2023
Year Source
2023 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C17H32N4O4/c1-11(2)10-12(19)16(23)21-9-5-7-14(21)15(22)20-13(17(24)25)6-3-4-8-18/h11-14H,3-10,18-19H2,1-2H3,(H,20,22)(H,24,25)/t12-,13-,14-/m0/s1

InChIKey=YRRCOJOXAJNSAX-IHRRRGAJSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001





Database reference:
ChEBI: ID 159465

Metabolomics Workbench: ID 83347

PubChem: CID 145456506