BIOPEP-UWM: Report

ID 10571
Name ACE inhibitor
sequence
SFYPDY

Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 790.8137 Monoisotopic mass 790.3162
IC50 :
104.70 µM



Bibliographic data:
Authors
Wu C.-L., Ni Z.-F., Kuang X.-Y., Li M.-F., Zong M.-H., Fan X.-D., Lou W.-Y.
Title
Novel multitarget ACE inhibitory peptides from bovine colostrum immunoglobulin G: cellular transport, efficacy in regulating endothelial dysfunction, and network pharmacology studies. J. Agric. Food Chem., 72, 4155–4169, 2024
Year Source
2024 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CO)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C39H46N6O12/c40-27(21-46)34(51)41-28(17-22-5-2-1-3-6-22)35(52)43-30(18-23-8-12-25(47)13-9-23)38(55)45-16-4-7-32(45)37(54)42-29(20-33(49)50)36(53)44-31(39(56)57)19-24-10-14-26(48)15-11-24/h1-3,5-6,8-15,27-32,46-48H,4,7,16-21,40H2,(H,41,51)(H,42,54)(H,43,52)(H,44,53)(H,49,50)(H,56,57)/t27-,28-,29-,30-,31-,32-/m0/s1

InChIKey=OFRSOILKYAOBDU-JNRWAQIZSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides




Database reference: