BIOPEP-UWM: Report

ID 10580
Name ACE inhibitor
sequence
{GABA}{GABA}P

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 285.3385 Monoisotopic mass 285.1683
IC50 :
3.40 µM



Bibliographic data:
Authors
Qian B., Tian C., Huo J., Ding Z., Xu R., Zhu J., Yu L., Villarreal O. D.
Title
Design and evaluation of four novel tripeptides as potent angiotensin converting enzyme (ACE) inhibitors with anti-hypertension activity. Peptides, 122, 170171, 2019
Year Source
2019 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCCCC(=O)NCCCC(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C13H23N3O4/c14-7-1-5-11(17)15-8-2-6-12(18)16-9-3-4-10(16)13(19)20/h10H,1-9,14H2,(H,15,17)(H,19,20)/t10-/m0/s1

InChIKey=MHLNQBBEZHBNIZ-JTQLQIEISA-N

Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


{GABA} - γ-Aminobutyric acid; ID 196 in the BIOPEP-UWM repository of amino acids and modifications



Database reference: