BIOPEP-UWM: Report

ID 10584
Name Tripeptidyl peptidase II inhibitor
sequence
GF
Function:
Inhibitor of Tripeptidyl-peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
2
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 222.2399 Monoisotopic mass 222.1001
EC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F.
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C11H14N2O3/c12-7-10(14)13-9(11(15)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)(H,15,16)/t9-/m0/s1

InChIKey=JBCLFWXMTIKCCB-VIFPVBQESA-N


Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 7591).
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8782)
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9488)
Inhibitor of Acylaminoacyl peptidase (EC 3.4.19.1) (MEROPS ID: S09.004) according to the BIOPEP-UWM database of bioactive peptides, the BRENDA database
Antimalarial peptide according to the ParaPep database


Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 19), the BitterDB database, the ChEMBL database, the EROP-Moscow database (ID E03703), the PubChem database


Database reference:
ACToR: ID 3321-03-7

AHTPDB: ID 1112; 1383; 1402; 1421; 1681; 1813; 2657; 2791; 2936; 3023; 3176; 3483; 3796; 3841; 3918; 4232; 4430; 4502; 4697; 5149; 5427; 5455; 5744; 6577

BindingDB: ID 50188491

BioPepDB: ID biopep00334

BIOPEP-UWM database of bioactive peptides: ID 7591, 8782, 9488

BIOPEP-UWM database of sensory peptides and amino acids: ID 19

BitterDB: ID 835

BRENDA: Ligand Gly-Phe

ChEBI: ID 73912

ChEMBL: ID CHEMBL299889

ChemIDplus: ID 3321-03-7

ChemSpider: ID 83909

ECHA: compound N-glycyl-3-phenylalanine

eChemPortal: ID 3321-03-7

EROP-Moscow: ID E03703; E09345

Golm Metabolome Database: ID M001062

J-GLOBAL: ID 200907093284113983

MassBank: ID MT000058

Metabolights: ID MTBLC73912

MetaCyc: compound glycyl-L-phenylalanine

NIAID: ID 335273, 335277

Nikkaji: ID J149.622K

NIST Webbook: compound Glycyl-L-phenyl alanine

ParaPep: ID 1161

Pitt Quantum Repository: compound Glycyl-Phenylalanine

PubChem: CID 92953

SATPdb: ID satpdb12994

SDBS: ID MS-NW-2034; NMR-CDS-03-391

ZINC: ID ZINC01569529