BIOPEP-UWM: Report

ID 10596
Name Antibacterial peptide
sequence
K{G[3!K-m]}L{G[3!L-m]}K{G[3!L-m]}L{G[3!K-m]}L{G[3!L-m]}
Function:
Antibacterial
 
Number of residues
10
Activity code
ab
Activity :
antibacterial
Chemical mass 1209.6456 Monoisotopic mass 1208.8921
EC50 :
0.00 µM


Bibliographic data:
Authors
Bonvin E., Personne H., Paschoud T., Reusser J., Gan B.-H., Luscher A., Köhler T., van Delden C., Reymond J.-L.
Title
Antimicrobial peptide−peptoid hybrids with and without membrane disruption. ACS Infect. Dis., 9, 2593−2606, 2023
Year Source
2023 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCCN)C(=O)N(CCCCN)CC(=O)N[C@@]([H])(CC(C)C)C(=O)N(CC(C)C)CC(=O)N[C@@]([H])(CCCCN)C(=O)N(CC(C)C)CC(=O)N[C@@]([H])(CC(C)C)C(=O)N(CCCCN)CC(=O)N[C@@]([H])(CC(C)C)C(=O)N(CC(C)C)CC(=O)O

InChI=1S/C60H116N14O11/c1-40(2)29-48(58(83)71(28-20-18-26-64)36-52(76)69-50(31-42(5)6)60(85)74(34-45(11)12)39-55(79)80)67-54(78)38-72(32-43(7)8)57(82)47(22-14-16-24-62)66-53(77)37-73(33-44(9)10)59(84)49(30-41(3)4)68-51(75)35-70(27-19-17-25-63)56(81)46(65)21-13-15-23-61/h40-50H,13-39,61-65H2,1-12H3,(H,66,77)(H,67,78)(H,68,75)(H,69,76)(H,79,80)/t46-,47-,48-,49-,50-/m0/s1

InChIKey=VGDVIRCSQAHMCA-IQLYOATCSA-N

{G[3!L-m]} - N-Isobutylglycine (ID 221 in the BIOPEP-UWM repository of amino acids and modifications)
{G[3!K-m]} - N-(4-Aminobutyl)glycine (ID 222 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference: