BIOPEP-UWM: Report

ID 10599
Name Antibacterial peptide
sequence
kkLLkLLkLLL
Function:
Antibacterial
 
Number of residues
11
Activity code
ab
Activity :
antibacterial
Chemical mass 1322.8028 Monoisotopic mass 1321.9759
EC50 :
0.00 µM


Bibliographic data:
Authors
Personne H., Paschoud T., Fulgencio S., Baeriswyl S., Köhler T., van Delden C., Stocker A., Javor S., Reymond J.-L.
Title
To fold or not to fold: Diastereomeric optimization of an α‑helical antimicrobial peptide. J. Med. Chem., 66, 7570−7583, 2023
Year Source
2023 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@]([H])(CCCCN)C(=O)N[C@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)O

InChI=1S/C66H127N15O12/c1-38(2)31-49(78-62(88)51(33-40(5)6)75-57(83)46(24-16-20-28-68)72-56(82)45(71)23-15-19-27-67)60(86)73-47(25-17-21-29-69)58(84)76-52(34-41(7)8)63(89)79-50(32-39(3)4)61(87)74-48(26-18-22-30-70)59(85)77-53(35-42(9)10)64(90)80-54(36-43(11)12)65(91)81-55(66(92)93)37-44(13)14/h38-55H,15-37,67-71H2,1-14H3,(H,72,82)(H,73,86)(H,74,87)(H,75,83)(H,76,84)(H,77,85)(H,78,88)(H,79,89)(H,80,90)(H,81,91)(H,92,93)/t45-,46-,47-,48-,49+,50+,51+,52+,53+,54+,55+/m1/s1
InChIKey=DGQGNYLJKMPWRO-QHGPJNAHSA-N


Database reference: