BIOPEP-UWM: Report

ID 10606
Name Tubulin-tyrosine ligase inhibitor
sequence
YE

Function:
Inhibitor of Tubulin-tyrosine ligase (EC 6.3.2.25)
 
Number of residues
2
Activity code
ttl
Activity :
tubulin-tyrosine ligase inhibitor
Chemical mass 310.3018 Monoisotopic mass 310.1160
EC50 :
0.00 µM



Bibliographic data:
Authors
Raybin D., Flavin M.
Title
Enzyme which specifically adds tyrosine to the alpha chain of tubulin. Biochemistry, 16, 2189-2194, 1977
Year Source
1977 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)O

InChI=1S/C14H18N2O6/c15-10(7-8-1-3-9(17)4-2-8)13(20)16-11(14(21)22)5-6-12(18)19/h1-4,10-11,17H,5-7,15H2,(H,16,20)(H,18,19)(H,21,22)/t10-,11-/m0/s1

InChIKey: PDSLRCZINIDLMU-QWRGUYRKSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8934)
Inhibitor of Glutamate carboxypeptidase (EC 3.4.17.11) (MEROPS ID: M20.001) according to the BRENDA database
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010) according to the BRENDA database
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9078)
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007) according to the BIOPEP-UWM database of bioactive peptides (ID 9433)
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10470)



Database reference:
AHTPDB: ID 1417

BioPepDB: ID biopep01551

BIOPEP-UWM database of bioactive peptides: ID 8934, 9078

BRENDA: Ligand Tyr-Glu

ChEBI: ID 74883

ChEMBL: ID CHEMBL1221519

ChemSpider: ID 5373208

J-GLOBAL: ID 200907003942622430

Metabolights: ID MTBLC74883

Nikkaji: ID J150.478I

PubChem: CID 7009628

SDBS: ID SDBS-9381

SureChEMBL: ID SCHEMBL1374181

ZINC: ID ZINC02384847