BIOPEP-UWM: Report

ID 10607
Name Tubulin-tyrosine ligase inhibitor
sequence
YY
Function:
Inhibitor of Tubulin-tyrosine ligase (EC 6.3.2.25)
 
Number of residues
2
Activity code
ttl
Activity :
tubulin-tyrosine ligase inhibitor
Chemical mass 344.3610 Monoisotopic mass 344.1367
EC50 :
0.00 µM


Bibliographic data:
Authors
Raybin D., Flavin M.
Title
Enzyme which specifically adds tyrosine to the alpha chain of tubulin. Biochemistry, 16, 2189-2194, 1977
Year Source
1977 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI= 1S/C18H20N2O5/c19-15(9-11-1-5-13(21)6-2-11)17(23)20-16(18(24)25)10-12-3-7-14(22)8-4-12/h1-8,15-16,21-22H,9-10,19H2,(H,20,23)(H,24,25)/t15-,16-/m0/s1

InChIKey: JAQGKXUEKGKTKX-HOTGVXAUSA-N


Inhibitor of Dipeptidyl peptidase IV (DPP IV) (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8948)
Inhibitor of Dipeptidyl peptidase III (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9476); the BRENDA database
Inhibitor of tyrosyl tRNA synthetase (EC 6.1.1.1) from Staphylococcus aureus according to the ChEMBL database; the PubChem database
Inhibitor of renin (EC 3.4.23.15) (MEROPS ID: A01.007) according to the BRENDA database
Inhibitor of angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9946)

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID: 33)


Database reference:
ACToR: ID 1050-28-8

AHTPDB: ID 5413

BindingDB: ID BDBM50081840

BioPepDB: ID biopep01645

BIOPEP-UWM database of bioactive peptides: ID 8948; 9476; 9946

BIOPEP-UWM database of sensory peptides and amino acids: ID 33

BRENDA: Ligand Tyr-Tyr

ChEBI: ID 60989

ChEMBL: ID CHEMBL95286

ChemIdPlus: ID 1050-28-8

ChemSpider: ID 63759

CTD: ID 1050-28-8

EROP-Moscow: ID E10447

J-GLOBAL: ID 200907087926120458

Metabolights: ID MTBLC60989

Nikkaji: ID J150.479G

PubChem: ID 70590

SATP: ID satpdb13867

SureChEMBL: ID SCHEMBL1574161

ZINC: ID ZINC02004481