BIOPEP-UWM: Report

ID 10626
Name Glutamate carboxypeptidase II inhibitor
sequence
{C2:0}DQ
Function:
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010)
 
Number of residues
3
Activity code
gluc2
Activity :
glutamate carboxypeptidase II inhibitor
Chemical mass 303.2679 Monoisotopic mass 303.1062
IC50 :
0.00 µM


Bibliographic data:
Authors
Robinson M. B., Blakely R. D., Couto R., Coyle J. T
Title
Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. J. Biol. Chem., 262, 14498-14506, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: CC(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)O

InChI=1S/C11H17N3O7/c1-5(15)13-7(4-9(17)18)10(19)14-6(11(20)21)2-3-8(12)16/h6-7H,2-4H2,1H3,(H2,12,16)(H,13,15)(H,14,19)(H,17,18)(H,20,21)/t6-,7-/m0/s1

InChIKey=FHLVSJCMOXYPEY-BQBZGAKWSA-N


{C2:0} - Acetic acid - N-terminal modification (ID 130 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference:
BRENDA: Ligand N-Acetyl-Asp-Gln

ChemSpider: ID 9897216

J-GLOBAL: ID 200907089808633591

Nikkaji: ID J862.461E

PubChem: CID 11722500

SureChEMBL: ID SCHEMBL10793247